Chris (Clive Owen) has just been released from prison. Frank (Billy Crudup), his cop brother, helps him by giving him a place to stay, finding him a job and trying to get him back with his wife Monica (Marion Cotillard). Chris tries to readjust to society, but is met only by distrust and contempt. To get money and start fresh with Natalie (Mila Kunis), a beautiful cashier he’s fallen for, he falls back into the criminal life by agreeing to carry out a hit. Frank, meanwhile, takes up with Vanessa (Zoe Saldana), who’s tied to Antony, a dangerous criminal whom he helped get locked up. At each meeting, the relationship between the two brother turns around their father, who clearly prefers Chris over Frank. Frank finally loses his patience and decides to drop his hopeless brother. Will he really be able do that?

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